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Rat Models of Prenatal and Adolescent Cannabis Exposure

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Marijuana (Cannabis sativa ) is the illicit drug most commonly used by two vulnerable populations relevant to neurodevelopment—pregnant women and teenagers. Human longitudinal studies have linked prenatal and adolescent cannabis exposure with long-term behavioral abnormalities as well as increased vulnerability to neuropsychiatric disorders in adulthood. Animal models provide a means of studying the neurobiological mechanisms underlying these long-term effects. This chapter provides an overview of the animal models we have used to study the developmental impact of cannabis.
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