Inhibition of APP Synthesis by Ribozymes and Oligonucleotides in a Coupled Reticulocyte Transcription Translation System
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Alzheimer’s disease (AD) is a progressive neurodegenerative disorder that results in dementia, and ultimately in the death of its victims. In the United States, AD is the fourth leading cause of death, and without a forseeable means of prevention, or effective treatment this will likely increase as the population ages.









