丁香实验_LOGO
登录
提问
我要登录
|免费注册
点赞
收藏
wx-share
分享

Anti-claudin-4-Conjugated Highly Luminescent Nanoparticles as Biological Labels for Pancreatic Cancer Sensing

互联网

732
Anti-claudin-4, whose corresponding antigen receptors are known to be overexpressed in both primary and metastatic human pancreatic cancer, is utilized for targeted delivery and imaging of pancreatic cancer. In this protocol, we describe the use of quantum dots (QDs) as sensitive optical contrast agent for imaging pancreatic cancer in vitro and in vivo by using anti-claudin-4 as targeting ligands. The claudin-4-mediated targeting is demonstrated in using both in vitro confocal microscopy and in vivo tumor imaging system. This targeted QD platform will be further modified for the purpose of developing as an early detection imaging tool for pancreatic cancer.
ad image
提问
扫一扫
丁香实验小程序二维码
实验小助手
丁香实验公众号二维码
扫码领资料
反馈
TOP
打开小程序