Molecular Diagnosis of Fanconi Anemia and Dyskeratosis Congenita

The inherited bone marrow (BM) failure syndromes Fanconi anemia (1 ) and dyskeratosis congenita (2 ) are genetic disorders in which patients develop BM failure at a high frequency, usually in association with a number of somatic abnormalities. They are the best characterized and the most common of this group of disorders.