CD79a/CD79b分子
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CD79a/CD79b 分子
CD79a
常用单克隆抗体或代号： Iga ,mb- 1
主要表达细胞： B [B]
分子质量(kDa)和结构： 33(IgSF)
功 能： BCR复合体组成成分
CD79b
常用单克隆抗体或代号： Igb ,B29
主要表达细胞： B [B]
分子质量(kDa)和结构： 39(IgSF)
功 能： BCR复合体组成成分
CD79a
Encodes the Ig-alpha protein of the B-cell antigen receptor; receptor also includes Ig-beta protein, surface immunoglobulin
Expressed early in B-cell differentiation (often positive when mature B-cell markers are negative); also expressed in plasma cells
Uses: positive in acute lymphoblastic leukemia, small B cell lymphoproliferative disorders when CD20 may be negative; more consistently preserved in infarcted lymphomas than CD20, Archives 2003;127:60
Positive staining: B cell lymphomas, lymphocyte-predominant Hodgkin lymphoma, classic Hodgkin lymphoma
Micro images: Warthin-Finkeldey giant cells in measles related appendicitis (Figure C), infarcted lymphomas, figures 2 & 6
CD79b
Encodes the Ig-beta protein of the B-cell antigen receptor; receptor also includes Ig-alpha protein, surface immunoglobulin
