丁香实验_LOGO
登录
提问
我要登录
|免费注册
点赞
收藏
wx-share
分享

Knockin Approaches

互联网

562
Molecular genetic approaches toward the study of gene function in mice have traditionally relied on either overexpression or gene ablation using transgenic or knockout mouse strategies, respectively. More recently, the knockin approach, which often combines features of both techniques, has allowed a more subtle analysis of genes. The protein coding region of a gene can be replaced by, e.g., a reporter gene, or a homologous gene of a different species, or related genes from the same organism. Even (point) mutations can be introduced into a gene, affecting the gene product itself.
ad image
提问
扫一扫
丁香实验小程序二维码
实验小助手
丁香实验公众号二维码
扫码领资料
反馈
TOP
打开小程序