Knock-In Approaches
互联网
1012
Molecular genetic strategies to study gene function in mice or to generate a mouse model for a human disease are continuously under development. The application and importance of knock-in approaches are increasing. This chapter elaborates on novel developments for the generation of knock-in mice. Special emphasis is given to recombinase-mediated cassette exchange, a new emerging knock-in strategy that enables easy generation of a series of different knock-in mutations within one gene.
![基因敲除HR靶向载体[MCS 1-EF 1a-GFP-T2 A-Puro-pA-MCS 2]-Gene Knock-Out HR Targeting Vector [MCS1-EF1a-GFP-T2A-Puro-pA-MCS2]](https://img1.dxycdn.com/p/s14/2025/0226/793/4490333375672954981.jpg!wh200)
