Somatic Cell Knockouts of Tumor Suppressor Genes
互联网
458
Gene targeting is the modification of specific DNA sequences in a living organism. Three requirements must be met in order for gene targeting to be successful (1 ). The process must be directed, so that it affects only the locus of choice. The targeting procedure requires specificity, such that a predetermined sequence can be inserted or substituted at the target locus. Finally, the process should be efficient.
