CD50分子
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CD50 分子
CD50
常用单克隆抗体或代号： 101- 1D2,140- 11;(ICAM- 3)
主要表达细胞： Leu [AS]
分子质量(kDa)和结构： gp120(IgSF)
功 能： 粘附,CD11a- CD11b/CD18配基,信号转导和共刺激
CD50
Aka ICAM-3; ligand for LFA-1 (CD54)
Provides adhesion signals important in B-T cell interactions
Important in MHC restricted interaction between T cells and target cells
Regulates leukocyte morphology
Positive staining (normal): leukocytes, epidermal Langerhans cells, endothelial cells
Negative staining: non-hemaoietic cells
