Single Nucleotide Polymorphism Genotyping in MMP Genes: The 5 Nuclease Assay
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Many molecular genetic studies of human diseases involve determining the genotypes for single nucleotide polymorphisms. This chapter summarises a number of different techniques for the single nucleotide polymorphism genotyping which can be applied to MMP genes. The chapter also provides a protocol and technical notes for the 5ʹ-nuclease assay, one of the most commonly used genotyping techniques.
