CD65/CD65s分子
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CD65/CD65s 分子
CD65
常用单克隆抗体或代号： VIM2,HE10,CF4
主要表达细胞： PMN [M]
分子质量(kDa)和结构： 岩藻糖基神经节苷脂
功 能： 中性粒细胞活化
CD65s
常用单克隆抗体或代号： 88H7
主要表达细胞： PMN,M [M]
分子质量(kDa)和结构： Siapoly- sialyl- n- acetylactosamide
功 能：与吞噬作用有关
CD65
Aka VIM2, ceramide-dodecasaccharide
Adhesive molecule that appears to be significant risk factor for extravascular AML infiltration
Positive staining (normal): myeloid cells, monocytes
CD65s
Widely used for acute leukemia cell typing and to identify a subset of pre-pre-B ALL
Aka sialylated-CD65
May inhibit phagocytosis
Positive staining (normal): granulocytes, monocytes
Positive staining (disease): myeloid leukemia cells
