Electrospinning Tubular Scaffolds with Tissue-Like Mechanical Properties and Biomimetic Surface Features

Electrospinning is a useful technique for generating scaffolds composed of nano- and/or microfibers. Through an innovative modification of the cylindrical target mandrel it is possible to create macrostructural or microstructural invaginations. The former provides complex bulk mechanical behavior reminiscent of native soft tissue; the latter leads to a surface topography reminiscent of intestinal villi.