• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        Detection of Microsatellite Instability

        互联网

        379
        In 1993, three groups independently discovered that the lengths of microsatellites in tumors could vary from the normally constant pattern defined at birth (5 5 ) (see review in ref. 4 ). This discovery has been designated either microsatellite instability (MSI) or replication errors (RER). A recent international consensus conference convened by the National Cancer Institute defined MSI/RER as “a change in length due to either insertion or deletion of repeating units, in a microsatellite within a tumor when compared to normal tissue” (5 ). Microsatellites are regions of repetitive DNA in which the repeating unit is small, varying in length from 1 to 6 nucleotides, and in which the number of repeating units in a microsatellite can vary from 10–60 (6 7 ). Because microsatellite lengths generally vary from person to person, they have received widespread use in forensics, gene mapping, parentage testing,
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序