Chick Embryotoxicity Screening Test (CHEST I and II)
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The chick embryo has been used for the study of experimental teratogenicity by various techniques (1
–4
). This chapter describes a method developed by Jelinek (5
,6
) that combines a standardized technique (CHEST I) with other techniques (CHEST II); it allows the administration of small
amounts of test compound and the measurement of a quantitative endpoint (CHEST I).
