• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        Identification of Mutations in the Retinoblastoma Gene

        互联网

        453
        Mutations in the retinoblastoma gene (RBl) predispose to the formation of ocular tumors. Following the cloning of RBI in 1986 (1 ), polymorphic restriction enzyme sites within RBl were used to “track” the mutant gene within affected families using linkage analysis (2 , 3 ). This approach, however, was unsuitable for most retinoblastoma (Rb) patients because only 16% have a family history of Rb (4 ). In recent years, it has become possible to detect mutations in nucleic acids. The ability to detect mutations in RBl has important implications for Rb patients because it means that individuals predisposed to Rb but with no previous family history of the disease can now be screened for mutations.
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序