Restriction Fragment-Length Polymorphisms
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Knowledge of eukaryotic-gene structure has grown exponentially over the past two decades, mainly owing to the mtroduction
of new molecular techniques These have enabled the manipulation and analysis of the DNA molecule and led to the identificatlon
of mutations causing single gene disorders An important factor in the development of such techniques was the discovery of
a family of bacterial enzymes, the restriction endonucleases (1
)
