• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        Diagnosisand Investigation of Diarrheagenic Escherichia coli

        互联网

        619
        Although most Escherichia coli are harmless commensals of the human intestine, certain specific, highly-adapted E. coli strains are capable of causing urinary tract, systemic or enteric/diarrheagenic infection. Diarrheagenic E coli are divided into six distinct categories, or pathotypes, each with a distinct pathogenic scheme (Table 1 ). Combined, diarrheagenic E coli have emerged as perhaps the most important enteric pathogens of man. In the developing world, the E coli categories account for more cases of gastroenteiltis among infants than any other cause (1 ) In addition, E coli are also the most common cause of traveller’s diarrhea, which afflicts more than one million travellers to the developing world annually (1 ). Enterohemorrhagic E coli (EHEC) are the cause of hemolytic uremic syndrome (HUS), which has become a major foodborne threat in many parts of the developed world (2 ).
        Table 1  Categories of Diarrheagenic E. coli

        Category

        Toxins

        Invasion

        Virulence plasmid

        Adhesin

        Clinical syndrome

        ETEC

        LT, ST

        Many

        CFA/I, CFA/II, CFA/IV, others

        Watery diarrhea

        EPEC

        +

        60 MDa

        Bundle-forming pilus

        Watery diarrhea of infants

        EHEC

        SLT-1, SLT-2

        60 MDa a

        Intimin, Fimbriae a

        Hemorrhagic colitis, HUS

        EAEC

        EAST1 a

        ?

        65 MDa a

        AAF/I, AAF/I

        Watery, persistent diarrhea

        EIEC

        EIET a

        +++

        140 MDa

        Ipa’s(?)

        Watery diarrhea, dysentery

        DAEC

        ?

        ?

        ?

        F1845 a

        Watery diarrhea

        a Role in pathogenesis unproven
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序