Detection and Molecular Cloning of the Extreme 3-End of HCV
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The 3′-end region of the HCV genome is composed of three characteristic elements: conventional 3′-untranslated region, subsequent poly (U) stretch, and a newly identified 3′-terminal sequence named the 3′X tail (1 ,2 ). The 3′X tail is thought to be a common structure of the HCV genome, and should have important roles in initiation and regulation of the genomic replication of HCV.
