Outer Membrane Protein Purification
互联网
705
The major outer membrane proteins (OMPs) from Neisseria meningitidis , which are expressed at high levels, are subdivided in five classes based on molecular weight (1 ,2 ) (see Table 1 ).
Table 1 Major Meningococcal Outer-Membrane Proteins
|
Outer-membrane proteins |
Name |
Molecular maass |
Function/characteristics |
|---|---|---|---|
|
Class 1 |
PorA |
44–47 kDa |
Por in |
|
Class 2/3 |
PorB |
37–42 kDa |
Por in |
|
Class 4 |
Rmp |
R eductionm odifiablep rotein, unknown |
|
|
Class 5 |
Opa |
26–30 kDa |
Adhesion,opa city protein |
|
Opc |
25 kDa |
Invasion, opacity protein |
|
|
Iron-regulated proteins |
Mirp |
37 kDa |
Iron acquisition (?);m ajori ron-r egulatedp rotein |
|
FrpB |
70 kDa |
Ferric enterobactin receptor (also FetA) |
Adapted from ref. (1 ).
