Modeling Calcium-Overload Mediated Necrosis in Drosophila

互联网2014-02-13

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Necrotic cell death (necrosis) occurs in many acute-onset diseases. However, our poor understanding of its mechanism has greatly limited medical interventions. Here we describe two methods to establish necrosis models in Drosophila . Our strategy is to overload calcium by expression of leaky cation channels.

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