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An Immunochemical Assay for Detecting Transition of B-DNA to Z-DNA

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605
The enzyme immunoassay technique described below is a simple and sensitive method to detect left-handed Z-DNA formation in synthetic polynucleotides, recombinant plasmids, and native DNAs. This method utilizes the differences in the antigenic properties of right-handed B-DNA and left-handed Z-DNA.
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