The Purification of Mouse Hematopoietic Stem Cells at Sequential Stages of Maturation
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Hematopoietic stem cells (HSCs) are rare, self-renewing progenitors that give rise to all lineages of blood cells. HSCs can
be found in all hematopoietic organs, from the para-aortic mesoderm (1
),(2
) and yolk sac (3
),(4
) in fetuses to the bone marrow (reviewed in ref. 5
), blood and spleens of adults.
