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Analysis of Anabolic Drugs by Direct Aqueous Supercritical Fluid Extraction Coupled On-Line with High-Performance Liquid Chromatography

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The analysis of drugs and their metabolites in biological fluids represents an essential role in pharmaceutical and toxicology studies. High performance liquid chromatography (HPLC) has emerged as a particularly powerful analytical technique for drug analysis since many water soluble compounds are too involatile and/or thermally labile to be analyzed by gas chromatography.
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