• 我要登录|
  • 免费注册
    |
  • 我的丁香通
    • 企业机构:
    • 成为企业机构
    • 个人用户:
    • 个人中心
  • 移动端
    移动端
丁香通 logo丁香实验_LOGO
搜实验

    大家都在搜

      大家都在搜

        0 人通过求购买到了急需的产品
        免费发布求购
        发布求购
        点赞
        收藏
        wx-share
        分享

        Isolation and Characterization of Resident Mesenchymal Stem Cells in Human Glomeruli

        互联网

        618
        We recently found that human glomeruli deprived of the Bowman’s capsule contain a population of CD133 CD146+ cells that coexpress the typical mesenchymal stem cells (MSCs) markers (such as CD29, CD105, and CD73) and renal specific stem cell markers (such us CD24 and Pax2). This population exhibited in vitro self-renewal capability, clonogenicity, and multipotency. Beside to osteogenic, adipogenic, and chondrogenic differentiation, these cells when cultured in appropriate culture conditions were able to differentiate into endothelial cells, epithelial cells expressing podocytes markers, and mesangial cells. These populations may have a role in the physiological cell turnover and/or in the response to renal injury. Herein, we present a review of the experimental procedures used for isolation and characterize MSCs resident in human adult glomeruli.
        ad image
        提问
        扫一扫
        丁香实验小程序二维码
        实验小助手
        丁香实验公众号二维码
        扫码领资料
        反馈
        TOP
        打开小程序