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        The Application of PCR to the Detection of M. tuberculosis in Sputum Samples

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        Human tuberculosis (TB) resulting from Mycobacterium tuberculosis and occasionally Mycobacterium bovis infection had been in decline for many decades, in the western world, owing to the advent of effective anti-microbial therapies and good public health programs that have controlled the spread of the disease. Nonetheless, there are currently in excess of one billion indivrduals infected with M. tuberculosis . TB accounts for approx 25% of all preventable deaths worldwide, resulting in more than 3.5 million deaths annually (1 ).
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