Gardiquimod

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Gardiquimod

CAS No. : 1020412-43-4

MCE 国际站：Gardiquimod

产品活性：Gardiquimod，一种咪唑啉类似物，TLR7/8 激动剂。Gardiquimod 可抑制巨噬细胞和活化外周血单个核细胞 (PBMCs) 的 HIV-1 感染。当浓度低于 10 μM 时，Gardiquimod 特别激活 TLR7。

研究领域：Immunology/Inflammation  |  Anti-infection

作用靶点：Toll-like Receptor (TLR)  |  HIV

In Vitro: Gardiquimod (6-60 μM ) significantly inhibits cDNA synthesis by HIV-1 reverse transcriptase.

In Vivo: Dendritic cells (DCs) in combination with Gardiquimod (1 mg/kg per mouse; i.p.; daily for 7 days) improves the anti-tumor effects of NK cells.

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