yGsy2p-IN-H23

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yGsy2p-IN-H23

CAS No. : 1269190-98-8

MCE 国际站：yGsy2p-IN-H23

产品活性：yGsy2p-IN-H23 是一种有效的酵母糖原合酶 2 (yGsy2p) 抑制剂，对人糖原合酶 1 (hGYS1) 的 IC₅₀ 为 875 µM。yGsy2p-IN-H23 结合在 yGsy2p 的尿苷二磷酸葡萄糖结合口袋内。yGsy2p-IN-H23 用于糖原储存疾病 (GSDs) 的相关研究。

研究领域：Others

作用靶点：Others

In Vitro: yGsy2p-IN-H23 (compound H23) has IC₅₀ values against either hGYS1Δ634S8,11N or wild-type hGYS1 were 161 μM and 875 μM, respectively. yGsy2p-IN-H23 exhibits IC₅₀ values of 280 μM and 263 μM in the absence and presence of G6P for yGsy2p against yeast and human glycogen synthase (GS),? respectively. yGsy2p-IN-H23 is not in direct competition with G6P.

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