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- 详细信息
- 技术资料
- 保存条件：
Pure form: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 库存：
货期：1-2天
- 供应商：
MedChemExpress LLC
- CAS号：
10458-14-7
- 规格：
10 mM * 1 mL/5 g/10 g/25 g/50 g/100 g/250 g/500 g/1000 g
| 规格： | 10 mM * 1 mL | 产品价格： | ￥110.0 |
|---|---|---|---|
| 规格： | 5 g | 产品价格： | ￥100.0 |
| 规格： | 10 g | 产品价格： | ￥151.0 |
| 规格： | 25 g | 产品价格： | ￥277.0 |
| 规格： | 50 g | 产品价格： | ￥402.0 |
| 规格： | 100 g | 产品价格： | ￥583.0 |
| 规格： | 250 g | 产品价格： | ￥1020.0 |
| 规格： | 500 g | 产品价格： | ￥1428.0 |
| 规格： | 1000 g | 产品价格： | ￥2000.0 |
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Menthone
CAS No. : 10458-14-7
MCE 国际站：Menthone
产品活性：Menthone，一种可以从植物和薄荷油中分离得到的具有口服活性的单萜，具有抗菌、抗肿瘤、抗氧化和抗病毒特性。Menthone 是精油的主要挥发性成分，在曼氏血吸虫感染和类风湿关节炎中具有抗炎特性。
研究领域：Anti-infection | Others
作用靶点：Parasite | Others
In Vitro: Menthone (0.05-500 μM, 48 h) has optimal concentration for murine primary lung mast cells are 0.5, 5 and 50 μM.
Menthone (0.5-50 μM, 48 h) inhibits the secretion of proinflammatory cytokine TNF-α and have anti-inflammatory potential to LPS-stimulated lung mast cells.
Menthone (100 μM, 24 h) inhibits activation of the key transcription factor STAT1 of IFN-I signaling and promotes Tyk2 polyubiquitination to reduce Tyk2 protein levels in 2fTGH cells.
In Vivo: Menthone (100 mg/kg, Articulus injection, 14 days) inhibits the expression of Th1 and Th17 cells.
Menthone (8-200 mg/kg, i.g. , daily, 5 weeks) improves the allergic inflammatory statu of the lungs and airways in OVA-sensitized and challenged allergic asthmatic inflammation mouse model by modulating the Th2-biased immune balance and mitigating mast cell degranulation.
Menthone (100 mg/kg, Articulus injection, 14 days) contributes to the relief of local inflammation of rheumatoid arthritis in CIA mice.
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