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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Mouse Translocator protein (Tspo)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Mouse Translocator protein (Tspo)品名简称:
Recombinant Mouse Tspo protein货号:
CSB-CF025168MO规格:
20μg价格:
9720LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 85% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
TspoUniprot No.:
P50637别名:
Mitochondrial benzodiazepine receptor (PKBS) (Peripheral-type benzodiazepine receptor) (PBR) (Bzrp) (Mbr)种属:
Mus musculus (Mouse)蛋白长度:
Full Length来源:
in vitro E.coli expression system分子量:
21.7 kDa表达区域:
1-169aa氨基酸序列:
MPESWVPAVGLTLVPSLGGFMGAYFVRGEGLRWYASLQKPSWHPPRWTLAPIWGTLYSAMGYGSYIVWKELGGFTEDAMVPLGLYTGQLALNWAWPPIFFGARQMGWALADLLLVSGVATATTLAWHRVSPPAARLLYPYLAWLAFATVLNYYVWRDNSGRRGGSRLPE蛋白标签:
N-terminal 10xHis-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
Can bind protoporphyrin IX and may play a role in the transport of porphyrins and heme. Was initially identified as peripheral-type benzodiazepine receptor; can also bind isoquinoline carboxamides. Promotes the transport of cholesterol across mitochondrial membranes and may play a role in lipid metabolism, but its precise physiological role is controversial. According to some reports, it is not required for steroid hormone biosynthesis.功能2:
/文献:
"High-throughput sequence identification of gene coding variants within alcohol-related QTLs." Ehringer M.A., Thompson J., Conroy O., Xu Y., Yang F., Canniff J., Beeson M., Gordon L., Bennett B., Johnson T.E., Sikela J.M. Mamm. Genome 12:657-663(2001)研究领域:
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文献和实验Animal Models of Anxiety and Depression
, for example, have been particularly useful in the preclmical testing of benzodiazepme-type anxiolytics, in studying the functional relevance of the GABAA -benzodiazepine receptor system, and in characterizing the effects of benzodiazepine antagonists (e.g., Ro
Saturation Assays of Radioligand Binding to Receptors and Their Allosteric Modulatory Sites
of the protocols (e.g., tissue preparation, buffers, assay termination techniques, incubation times, and temperatures). A saturation assay is presented to examine ligand binding to the benzodiazepine site on the GABA?A receptor, while a second protocol uses
高压进展。机制上,BACH1是脯氨酸羟化酶PHD2的底物,缺氧减少PHD2介导的BACH1羟基化,削弱其与E3泛素连接酶VHL的结合,抑制泛素-蛋白酶体降解,增强BACH1蛋白稳定性;BACH1入核后直接结合TGFBR2启动子促进其转录,增强下游SMAD3信号及细胞外基质基因表达。Bach1缺失显著减轻小鼠肺动脉高压表型,TGFBR2抑制剂可缓解BACH1过表达的促病变作用。该研究揭示了BACH1作为肺动脉高压治疗的潜在新靶点。 推荐产品 靶点 重组蛋白 货号 BACH
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