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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 保质期:
12个月
- 英文名:
Recombinant Human Serine protease inhibitor Kazal-type 1 (SPINK1), partial
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
10ug/20ug/50ug/100ug/200ug/500ug/1mg
| 规格: | 10ug | 产品价格: | ¥69.0 |
|---|---|---|---|
| 规格: | 20ug | 产品价格: | ¥139.0 |
| 规格: | 50ug | 产品价格: | ¥209.0 |
| 规格: | 100ug | 产品价格: | ¥349.0 |
| 规格: | 200ug | 产品价格: | ¥419.0 |
| 规格: | 500ug | 产品价格: | ¥559.0 |
| 规格: | 1mg | 产品价格: | ¥699.0 |
Research Areas
Cell BiologyUniprot ID
P00995Gene Names
SPINK1Alternative Name(s)
Pancreatic secretory trypsin inhibitor;Tumor-associated trypsin inhibitor;TATILead Time
3-7 business daysOrganism
Homo sapiens (Human)Source
E.coliExpression Region
19-79aaProtein Length
PartialTag Info
N-terminal 6xHis-GST-taggedTarget Protein Sequence
GNTGADSLGREAKCYNELNGCTKIYDPVCGTDGNTYPNECVLCFENRKRQTSILIQKSGPCMW
38.2 kDaPurity
Greater than 85% as determined by SDS-PAGE.Form
Lyophilized powder.If the size you ordered does not have lyophilized powder in stock, we will provide it in liquid formBuffer
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose.Reconstitution
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.Notes
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.风险提示:丁香通仅作为第三方平台,为商家信息发布提供平台空间。用户咨询产品时请注意保护个人信息及财产安全,合理判断,谨慎选购商品,商家和用户对交易行为负责。对于医疗器械类产品,请先查证核实企业经营资质和医疗器械产品注册证情况。
文献和实验An Integrated Approach for Monitoring Cell Senescence
Cellular senescence is considered as a crucial mechanism of tumor suppression that helps to prevent the growth of cells at risk for neoplastic transformation. In normal cells, cellular senescence induces an irreversible cell cycle arrest
编码的蛋白质ING的水平似乎与肿瘤侵袭性强度相对应,蛋白水平越低,神经胶质瘤恶性程度越高。,研究人员还描述了ING4是如何抑制向肿瘤提供营养的新血管生长。ING(INhibitor of tumor Growth,肿瘤生长抑制因子)是肿瘤抑制基因p53活动所必需的一个蛋白家族。由麻萨诸塞综合医院放射肿瘤学部Steele实验室的Igor Garkavtsev博士领导的研究小组搜索了一个基因数据库,目的是识别出与早先识别出的ING1结构类似的基因。 研究小组首先检查了50个处于各种恶性级别的肿瘤
, axin, and the tumor suppressor, adenomatouspolyposis coli (APC) protein (3) . In the absence of Wnt signaling,GSK-3 targets b-catenin for ubiquitin-mediated proteosomaldegradation by phosphorylation of b-catenin, axin, and APC (3) . Phosphorylation
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