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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.
- 保质期:
Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.
- 英文名:
Recombinant Mouse Nicotinamide riboside kinase 1 (Nrk1)
- 库存:
200
- 供应商:
武汉华美生物工程有限公司
- 规格:
20μg
英文名称:
Recombinant Mouse Nicotinamide riboside kinase 1 (Nrk1)品名简称:
Recombinant Mouse Nrk1 protein货号:
CSB-EP835569MO规格:
20μg价格:
2328LC-MS/Western Blot:
/SDS-PAGE:
(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.纯度:
Greater than 85% as determined by SDS-PAGE.内毒素:
Not test生物活性:
/基因名:
Nrk1Uniprot No.:
Q91W63别名:
NRK 1;NmR-K 1;Nicotinic acid riboside kinase 1;Ribosylnicotinamide kinase 1;RNK 1;Ribosylnicotinic acid kinase 1种属:
Mus musculus (Mouse)蛋白长度:
Full Length来源:
E.coli分子量:
26.4 kDa表达区域:
1-195aa氨基酸序列:
MKRFVIGIGGVTNGGKTTLAKSLQKHLPNCSVISQDDFFKPESEIDIDENGFLQYDVLEALNMEKMMSAVSCWMENPGSSAGPAALESAQGVPILIIEGFLLFNYKPLDTIWNRSYFLTVPYEECKRRRSTRVYEPPDPPGYFDGHVWPMYLKHRQEMSSITWDIVYLDGTRSEEDLFSQVYEDVKQELEKQNGL蛋白标签:
N-terminal 6xHis-tagged产品提供形式:
Liquid or Lyophilized powder缓冲液:
If the delivery form is liquid, the default storage buffer is Tris/PBS-based buffer, 5%-50% glycerol. If the delivery form is lyophilized powder, the buffer before lyophilization is Tris/PBS-based buffer, 6% Trehalose, pH 8.0.储存条件:
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.保质期:
The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.货期:
3-7 business days注意事项:
Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.功能1:
/功能2:
/文献:
/研究领域:
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文献和实验合作,近期在Aging Cell发表了一篇研究。该研究通过整合单细胞转录组、单核转录组和空间转录组测序,系统描绘了小鼠肝脏衰老过程中免疫微环境的时空动态演变,发现CD8⁺ T细胞耗竭具有门静脉区特异性空间富集特征,并鉴定出门静脉旁肝细胞中的LPIN1分子是诱导T细胞耗竭的关键调控因子。该现象在多种人类肝脏疾病中得到验证,为延缓肝脏衰老相关免疫功能障碍及治疗年龄相关肝病提供了潜在新靶点。 02 靶点:ZDHHC20 应用:为临床
Selecting, Acquiring, and Using Small Molecule Libraries for High‐Throughput Screening
. Mahasenan, K.V., Pavlovicz, R.E., Henderson, B.J., González‐Cestari, T.F., Yi, B., McKay, D.B., and Li, C. 2011. Discovery of Novel α4β2 Neuronal nicotinic receptor modulators through structure‐based virtual
,二价金属阳离子是绝对需要的. Beck et al报告,在抽提的细胞而不是完整的细胞中,锤头状核酶能有效地切割HBV的壳膜信号. 体外试验表明,经过蛋白K酶和酚抽提处理的细胞,随着MgCl2浓度的提高,胞外终浓度达5-10 mmol/L(胞内MgCl2浓度为l mmol/L)时,该酶的切割效率是最高的. 核酶一底物复合物活性是通过核酶结构的改变来实现的,MgCl2浓度的高低是诱导核酶结构变化的关键,因此细胞内MgCL2浓度可影响靶RNA(如HBV壳膜信号)的延伸. 由于HBV前基因组转录的结果
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