人TNFSF13B重组蛋白B lymphocyte stim

英文名称：

Recombinant Human Tumor necrosis factor ligand superfamily member 13B (TNFSF13B), partial (Active)

品名简称：

Recombinant Human TNFSF13B protein, partial (Active)

货号：

CSB-MP897523HU1

规格:

20μg

价格：

828

LC-MS/Western Blot：

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SDS-PAGE：

(Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

纯度：

Greater than 90% as determined by SDS-PAGE.

内毒素：

Less than 1.0 EU/μg as determined by LAL method.

生物活性：

①Measured by its binding ability in a functional ELISA. Immobilized TNFSF13B at 10 μg/ml can bind human BCMA (CSB-MP023974HU1), the EC50 of human TNFSF13B protein is 221.3-298.6 ng/ml.②Human SIRPA protein His/Myc tag (CSB-MP021334HU) captured on COOH chip can bind Human CD47 protein Fc tag (CSB-MP004940HU) with an affinity constant of 19.1 nM as detected by LSPR Assay.③Measured by its binding ability in a functional ELISA. Immobilized TNFSF13B at 2 μg/ml can bind TNFRSF13C（CSB-MP853495HU1）, the EC50 is 9.943-15.72 ng/ml.

基因名：

TNFSF13B

Uniprot No.：

Q9Y275

别名：

B lymphocyte stimulator （BLyS） （B-cell-activating factor） （BAFF） （Dendritic cell-derived TNF-like molecule） （TNF- and APOL-related leukocyte expressed ligand 1） （TALL-1）

种属：

Homo sapiens (Human)

蛋白长度：

Partial

来源：

Mammalian cell

分子量：

46.6 kDa

表达区域：

134-285aa

氨基酸序列：

AVQGPEETVTQDCLQLIADSETPTIQKGSYTFVPWLLSFKRGSALEEKENKILVKETGYFFIYGQVLYTDKTYAMGHLIQRKKVHVFGDELSLVTLFRCIQNMPETLPNNSCYSAGIAKLEEGDELQLAIPRENAQISLDGDVTFFGALKLL

蛋白标签：

N-terminal hFc-tagged

产品提供形式：

Lyophilized powder

缓冲液：

Lyophilized from a 0.2 μm sterile filtered PBS, 6% Trehalose, pH 7.4

储存条件：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

保质期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

货期：

3-7 business days

注意事项：

Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

功能1：

Cytokine that binds to TNFRSF13B/TACI and TNFRSF17/BCMA. TNFSF13/APRIL binds to the same 2 receptors. Together, they form a 2 ligands -2 receptors pathway involved in the stimulation of B- and T-cell function and the regulation of humoral immunity.

功能2：

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文献：

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研究领域：

Cancer

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