人IL13重组蛋白Interleukin-13;IL-13;Human Interleukin-13(IL13)(Active)蛋白产品图
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人IL13重组蛋白Interleukin-13;IL-13;

Human Interleukin-13(IL13)(Active)蛋白
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  • ¥1740
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  • CN
  • CSB-AP004321HU
  • 2026年01月20日
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    • 详细信息
    • 文献和实验
    • 技术资料
    • 保存条件:

      We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃.

    • 保质期:

      Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    • 英文名:

      Recombinant Human Interleukin-13 (IL13), partial (Active)

    • 库存:

      200

    • 供应商:

      武汉华美生物工程有限公司

    • 规格:

      10μg


    英文名称:

    Recombinant Human Interleukin-13 (IL13), partial (Active)

    品名简称:

    Recombinant Human IL13 protein, partial (Active)

    货号:

    CSB-AP004321HU

    规格:

    10μg

    价格:

    1740

    LC-MS/Western Blot:

    /

    SDS-PAGE:

    (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.

    纯度:

    Greater than 95% as determined by SDS-PAGE.

    内毒素:

    Less than 1.0 EU/μg as determined by LAL method.

    生物活性:

    The ED50 as determined in a cell proliferation assay using TF‑1 human erythroleukemic cells is 1.5-4.5 ng/ml.

    基因名:

    IL13

    Uniprot No.:

    AAH96139

    别名:

    Interleukin-13;IL-13;

    种属:

    Homo sapiens (Human)

    蛋白长度:

    Partial

    来源:

    Mammalian cell

    分子量:

    13.4 kDa

    表达区域:

    35-146aa

    氨基酸序列:

    GPVPPSTALRELIEELVNITQNQKAPLCNGSMVWSINLTAGMYCAALESLINVSGCSAIEKTQRMLSGFCPHKVSAGQFSSLHVRDTKIEVAQFVKDLLLHLKKLFREGQFN

    蛋白标签:

    C-terminal 6xHis-tagged

    产品提供形式:

    Lyophilized powder

    缓冲液:

    Lyophilized from a 0.2 μm filtered solution of PBS,PH7.4.

    储存条件:

    We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.

    保质期:

    The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20℃/-80℃. The shelf life of lyophilized form is 12 months at -20℃/-80℃.

    货期:

    5-10 business days

    注意事项:

    Repeated freezing and thawing is not recommended. Store working aliquots at 4℃ for up to one week.

    功能1:

    Interleukin-13 is also known as IL-13. It is a protein that in humans is encoded by the IL13 gene. Interleukin-13 is an immunoregulatory cytokine produced primarily by activated Th2 cells.It is involved in several stages of B-cell maturation and differentiation. It up-regulates CD23 and MHC class II expression, and promotes IgE isotype switching of B cells. This cytokine down-regulates macrophage activity, thereby inhibits the production of pro-inflammatory cytokines and chemokines. This cytokine is found to be critical to the pathogenesis of allergen-induced asthma but operates through mechanisms independent of IgE and eosinophils.

    功能2:

    Cytokine

    文献:

    /

    研究领域:

    Immunology

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      酸性粒细胞(Eosinophils)和中性粒细胞(Neutrophils)的增加最为剧烈,淋巴细胞也有一定程度增加;同时,嗜酸性粒细胞关键趋化因子Ccl11(Eotaxin-1)在肺部呈现剂量依赖性上调。 杯状细胞化生与黏液分泌增加 肺组织PAS染色(糖原染色)显示,AAV-IL13处理的小鼠气道上皮发生强烈的杯状细胞化生(Goblet cell metaplasia)和黏液过度分泌,高剂量下甚至引发严重的黏液栓塞;粘蛋白基因Muc5ac的表达量显著上调。   2、群转录组特征

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