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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
A synthetic peptide from the internal region of human PIK3CA.
- 亚型:
lgG
- 形态:
液体
- 保存条件:
-20℃
- 克隆性:
单克隆
- 标记物:
FITC
- 适应物种:
脊椎动物
- 保质期:
24个月
- 抗原来源:
蛋白
- 目录编号:
TD-26069
- 级别:
科研级
- 库存:
999
- 供应商:
武汉天德
- 宿主:
Mouse
- 应用范围:
ELISA, WB, IF, IHC
- 浓度:
1mg/ml
- 靶点:
PIK3CA
- 抗体英文名:
Anti-PIK3CA mouse monoclonal antibody
- 抗体名:
PIK3CA
- 规格:
100 μL
PIK3CA
Cat. #: TD-26069
Size: 100 µL
Gene Symbol: PIK3CA
Description: Anti-PIK3CA Mouse Monoclonal Antibody
Background: Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The catalytic subunit is encoded by the PIK3CA gene. It phosphorylates PtdIns, PtdIns4P and PtdIns(4,5)P2. The PIK3CA gene is one of the most frequently mutated genes in human cancers.
Immunogen: A synthetic peptide from the internal region of human PIK3CA.
Tested applications: ELISA, WB, IHC, IP
Recommended dilutions: ELISA: 1:1000-1:5000 WB: 1:1000-1:5000 IHC: 1:50-1:100
Concentration: 1 mg/ml
Host Species: Mouse
Clonality: Monoclonal
Purity: Purified from ascites
Format: Liquid
Storage buffer:
Preservative: no
Constituents: PBS (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 50% glycerol
Species Reactivity: Anti-PIK3CA antibody recognizes PIK3CA of vertebrates.
Storage Conditions: Store at -20°C. Avoid freeze / thaw cycles
Western blot:
Western blot analysis of recombinant PIK3CA protein. Purified His-tagged PIK3CA protein (Cat.#10162) were blotted with anti-PIK3CA mouse monoclonal antibody (Cat.# TD-26069)
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文献和实验cancers (4 -6 ) have already contributed to the identification of the putative oncogene PIK3CA (7 ).
); PIK3CA (16); RET (6) OncoCarta™ Panel 2.0 18 AKT1 (1); BRAF (8); CTTNB1 (21); FBX4 (5); FBXW7(5); FGFR2 (2); FGFR3 (1); GNAQ (2); KIT (43); KRAS (6); MAP2K1 (6); MAP
每周的科研聚焦如期而至,学术君为给大家带来新一期重磅研究和趣味科研,用最精炼的话语让你读懂文章的核心,让您快速了解自己领域的最新研究进展。
电荷燃烧癌变组织并从组织燃烧气味中获取信息的智能手术刀,iKnife。该团队最新的研究发现,可以利用 iKnife 分析肿瘤组织的代谢情况, 近实时诊断 PIK3CA 突变型乳腺癌。因为 PIK3CA 突变可以通过 mTORC2-PKCζ-cPLA2 信号通路促进花生四烯酸产生。除此之外,他们还发现通过抑制 cPLA2 和限制膳食脂肪摄入可以抑制 PIK3CA 诱导的肿瘤发生并促进 NK 细胞的浸润。 (Cell) 6. 「唇亡齿寒」,牙周炎治疗不及时能引发肠炎牙疼不是病,疼起来要人命,殊不知牙周
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