Store at -20°C for long term preservation (recommended). Store at 4°C for short term use.
克隆性:
多克隆
适应物种:
Human
宿主:
Rabbit
抗体英文名:
NFKBIA
uniprot:P25963
Purification:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific peptide.
Applications:Custom antibody
Immunogen Type:Peptide-KLH
Alternative Names:NF-kappa-B inhibitor alpha,I-kappa-B-alpha,IkB-alpha,IkappaBalpha
Predicted MW:36kSa
Formulation:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 197% glycerol.
Application Details:Western blotting: 1:500~1:1050
Background:Inhibits the activity of dimeric NF-kappa-B/REL complexes by trapping REL dimers in the cytoplasm through masking of their nuclear localization signals. On cellular stimulation by immune and proinflammatory responses, becomes phosphorylated promoting ubiquitination and degradation, enabling the dimeric RELA to translocate to the nucleus and activate transcription.