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- 详细信息
- 文献和实验
- 技术资料
- 免疫原:
26S Proteasome Regulatory Subunit 6B (PSMC4)
- 亚型:
26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody
- 形态:
26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody
- 保存条件:
建议收到产品后,储存温度为-20°C。避免重复冻融
- 克隆性:
见产品详情页面
- 标记物:
无
- 适应物种:
人,小鼠,大鼠
- 保质期:
根据订购时间与产品批次判定,欢迎联系艾美捷咨询确认
- 抗原来源:
重组蛋白
- 目录编号:
abx114742
- 级别:
见产品详情页面
- 库存:
见产品详情页面
- 供应商:
艾美捷
- 宿主:
兔
- 应用范围:
ELISA, WB, IHC
- 浓度:
关于浓度,请联系艾美捷客服确认
- 靶点:
26S Proteasome Regulatory Subunit 6B (PSMC4)
- 抗体英文名:
26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody
- 抗体名:
26S Proteasome Regulatory Subunit 6B (PSMC4)
- 规格:
50ul///150ul
产品名称:26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody-26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody
产品货号:abx114742 产品规格:50ul#150ul 应用类型:ELISA, WB, IHC
保存建议:26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody-26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody建议收到产品后,储存温度为-20°C。避免重复冻融
背景资料:26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody is a Rabbit Polyclonal antibody against 26S Proteasome Regulatory Subunit 6B (PSMC4). The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. This gene encodes a member of the triple-A family of ATPases that is a component of the 19S regulatory subunit and plays a role in 26S proteasome assembly. The encoded protein interacts with gankyrin, a liver oncoprotein, and may also play a role in Parkinson's disease through interactions with synphilin-1. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
点击:26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody-26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody查看更详细产品说明,更多应用、储存、价格、货期等信息请致电400-6800-868垂询Abbexa中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论,请点击查看艾美捷特色产品网站。
Abbexa总部位于英国剑桥的剑桥科学园,是一家专业的全球抗体供应商和蛋白质供应商,致力于为生命科学、药物开发和生物技术领域的科学家和研究者提供最佳的客户体验和高质量的产品。产品涵盖一抗、二抗、蛋白质、ELISA试剂盒、酶以及其他用于研究的试剂盒和工具。无论您是进行学术研究,药物开发,疾病研究还是其它生物学研究,Abbexa的单克隆抗体,多克隆抗体,蛋白质和生物试剂均旨在促进您的研究。如果很难找到合适的抗体来满足您的需求,Abbexa还提供了定制蛋白质,肽和抗体的生产渠道。
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关键词:26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody,26S Proteasome Regulatory Subunit 6B (PSMC4) Antibody,待更新
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文献和实验Studies of the Ubiquitin Proteasome System
of Unstable E3s in Bacterial Lysates Basic Protocol 25: Expression of E3s in Eukaryotic in Vitro Translation Systems Basic Protocol 26: Expression of Multi‐Subunit E3s Using a Baculovirus Expression System Support Protocol 5: Batch Purification of Multimeric E
In Vitro Reconstitution of CFTR Biogenesis and Degradation
is recognized by a large multicatalytic protease, the 26S proteasome. This proteolytic machine is formed through the ATP-dependent association of two multimeric components, the 20S proteasome and the 19S regulatory subunit. The 19S subunit recognizes
can be selectively inhibited by targeting the catalytic site with drug?like compounds. Notably, the mammalian 26S proteasome is associated with three major DUBs: RPN11, UCH37, and USP14. Because the ubiquitin ?chain?trimming? activity of USP14 can inhibit proteasome
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