Ubiquitin Carboxyl-Terminal Hy

产品名称：Ubiquitin Carboxyl-Terminal Hydrolase 28 (USP28) Antibody-Ubiquitin Carboxyl-Terminal Hydrolase 28 (USP28) Antibody

产品货号：abx031556

产品规格：80ul#400ul

应用类型：WB

保存建议：Ubiquitin Carboxyl-Terminal Hydrolase 28 (USP28) Antibody-Ubiquitin Carboxyl-Terminal Hydrolase 28 (USP28) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs), 1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.

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关键词：Ubiquitin Carboxyl-Terminal Hydrolase 28 (USP28) Antibody，Ubiquitin Carboxyl-Terminal Hydrolase 28 (USP28) Antibody，待更新