Insulin Degrading Enzyme (IDE)

产品名称：Insulin Degrading Enzyme (IDE) Antibody-Insulin Degrading Enzyme (IDE) Antibody

产品货号：abx001373

产品规格：20ul#50ul#100ul#200ul

应用类型：WB, IF/ICC

保存建议：Insulin Degrading Enzyme (IDE) Antibody-Insulin Degrading Enzyme (IDE) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：IDE Antibody is a Rabbit Polyclonal antibody against IDE. This gene encodes a zinc metallopeptidase that degrades intracellular insulin, and thereby terminates insulins activity, as well as participating in intercellular peptide signalling by degrading diverse peptides such as glucagon, amylin, bradykinin, and kallidin. The preferential affinity of this enzyme for insulin results in insulin-mediated inhibition of the degradation of other peptides such as beta-amyloid. Deficiencies in this protein's function are associated with Alzheimer's disease and type 2 diabetes mellitus but mutations in this gene have not been shown to be causitive for these diseases. This protein localizes primarily to the cytoplasm but in some cell types localizes to the extracellular space, cell membrane, peroxisome, and mitochondrion. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described but have not been experimentally verified.[provided by RefSeq, Sep 2009].

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关键词：Insulin Degrading Enzyme (IDE) Antibody，Insulin Degrading Enzyme (IDE) Antibody，待更新