MAPK8 / MAPK9 / MAPK10 (pT183

产品名称：MAPK8 / MAPK9 / MAPK10 (pT183 / Y185 / T221) Antibody-MAPK8 / MAPK9 / MAPK10 (pT183 / Y185 / T221) Antibody

产品货号：abx000327

产品规格：50ul#100ul#200ul

应用类型：WB, IF/ICC

保存建议：MAPK8 / MAPK9 / MAPK10 (pT183 / Y185 / T221) Antibody-MAPK8 / MAPK9 / MAPK10 (pT183 / Y185 / T221) Antibody建议收到产品后，储存温度为-20°C。避免重复冻融

背景资料：MAPK8/9/10 (pT183/Y185/T221) Antibody is a Rabbit Polyclonal antibody against MAPK8 (pT183/Y185), MAPK9 (pT183/Y185) and MAPK10 (T221). Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as JUN, JDP2 and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells By similarity. Phosphorylates heat shock factor protein 4 (HSF4). /Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. In T-cells, JNK1 and JNK2 are required for polarized differentiation of T-helper cells into Th1 cells. JNK2 isoforms display different binding patterns: a-1 and a-2 preferentially bind to c-Jun, whereas beta-1 and beta-2 bind to ATF2. However, there is no correlation between binding and phosphorylation, which is achieved at about the same efficiency by all isoforms. JUNB is not a substrate for JNK2 a-2, and JUND binds only weakly to it. /Responds to activation by environmental stress and pro-inflammatory cytokines by phosphorylating a number of transcription factors, primarily components of AP-1 such as c-Jun and ATF2 and thus regulates AP-1 transcriptional activity. Required for stress-induced neuronal apoptosis and the pathogenesis of glutamate excitotoxicity.

点击：MAPK8 / MAPK9 / MAPK10 (pT183 / Y185 / T221) Antibody-MAPK8 / MAPK9 / MAPK10 (pT183 / Y185 / T221) Antibody查看更详细产品说明，更多应用、储存、价格、货期等信息请致电400-6800-868垂询Abbexa中国区域授权总代理艾美捷科技有限公司。更多特色试剂盒、特色抗体以及特色试剂等产品评论，请点击查看艾美捷特色产品网站。

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关键词：MAPK8 / MAPK9 / MAPK10 (pT183 / Y185 / T221) Antibody，MAPK8 / MAPK9 / MAPK10 (pT183 / Y185 / T221) Antibody，待更新