【产品名称】
通用名称:阿狄科®胆汁酸检测试剂盒(小玻璃管,血清样本)光度学
英文名称:IDK® Bile Acids (Cuvettes) (Serum), photometric
【包装规格】
96人份/盒
【预期用途】
适用于血清中胆汁酸的测定。
仅供科研使用。
【背景知识】
胆汁酸是肝脏中胆固醇代谢的终产物,与胆汁的其他成分(如胆固醇、胆红素、磷脂和蛋白质)一起释放到十二指肠。
胆汁酸的重要功能是通过肠道排泄胆固醇,在小肠中吸收脂肪和脂溶性维生素以及刺激肠道蠕动。
每天分泌的大部分胆汁酸在回肠末端被重吸收,通过门静脉输送到肝脏,并再次随胆汁排出。这个过程,也称为肠肝循环,导致每天只有 3-5% 的胆汁酸从粪便中排出。
胆汁酸代谢紊乱可发生在肝肠循环的不同部位:
- 肝细胞中胆汁酸合成受损
- 肝内胆汁淤滞,例如由于胆汁运输中断 - 胆管肝外阻塞
- 肠道中胆汁酸吸收受损
- 肝脏中胆汁酸再摄取受损
- 肝细胞内的细胞内代谢(循环)受损
参考文献:
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