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- 详细信息
- 文献和实验
- 技术资料
- 库存:
100
- 供应商:
上海博湖
- 检测范围:
78-5000pg/ml
- 检测方法:
Sandwich ELISA, Double Antibody
- 应用:
46.9pg/ml
- 样本:
CYP3A4
- 规格:
96T
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文献和实验Evaluation of Cytochrome P450 Activities in Human Hepatocytes In Vitro
Major hepatic cytochrome P450 activities (CYP1A2, CYP2A6, CYP2B6, CYP2C9, CYP2C19, CYP2D6, CYP2E1, and CYP3A4) can be simultaneously examined in human hepatocytes by incubation with a cocktail of multiple specific probes. Cocktail strategy
Assessment of CYP3A4 Time-Dependent Inhibition in Plated and Suspended Human Hepatocytes
This chapter provides a step-by-step description of methodology used to assess time-dependent inhibition/inactivation (TDI) potential of cytochrome P450 3A4 (CYP3A4) by a test compound using human hepatocytes in a 96-well plate format. Human
Evaluation of Time-Dependent CYP3A4 Inhibition Using Human Hepatocytes
prediction algorithms have been developed, the accuracy has still improved little. This suggests alternate methods to collect input data may improve prediction robustness. Historically, human liver microsomes have been used to generate inhibition kinetic data
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