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- 详细信息
- 文献和实验
- 技术资料
- 保存条件:
Powder: -20°C, 3 years; 4°C, 2 years.In solvent: -80°C, 6 months; -20°C, 1 month.
- 英文名:
Deacetylated chitin (MW 150000); Poly(D-glucosamine) (MW 150000)
- 库存:
货期:1-2天
- 供应商:
MedChemExpress LLC
- CAS号:
9012-76-4
- 规格:
1 g/5 g/10 g
| 规格: | 1 g | 产品价格: | ¥500.0 |
|---|---|---|---|
| 规格: | 5 g | 产品价格: | ¥1250.0 |
| 规格: | 10 g | 产品价格: | ¥2000.0 |
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Chitosan (MW 150000)
CAS No. : 9012-76-4
MCE 国际站:Chitosan (MW 150000)
产品活性:Chitosan (MW 150000) (Deacetylated chitin (MW 150000)) 是衍生自几丁质的聚阳离子线性多糖,分子量为 150000。Chitosan 因其无毒,低致敏性,生物相容性和可生物降解性而被广泛使用。Chitosan 还具有抗肿瘤,抗细菌,抗真菌和抗氧化活性。
研究领域:Anti-infection
In Vitro: Chitosan (2 mg/mL; 48 hours; SKMEL28 and RPMI7951 cells) treatment presents a reduced growth potential.
Chitosan (2 mg/mL; 48 hours; RPMI7951 cells) treatment shows potent pro-apoptotic effects against RPMI7951 through the mitochondrial pathway.
Chitosan (2 mg/mL; 48 hours; RPMI7951 cells) treatment induces an up regulation of pro-apoptotic molecules such as Bax and a down regulation of anti-apoptotic proteins like Bcl-2 and Bcl-XL.
Low-molecular-weight chitosan can penetrate bacterial cell walls, bind with DNA and inhibit DNA transcription and mRNA synthesis, while high-molecular-weight Chitosan can bind to the negatively charged components on the bacterial cell wall. It forms an impermeable layer around the cell, changes cell permeability and blocks transport into the cell. Chitosan also can be used in water treatment, wound-healing materials, pharmaceutical excipient or drug carrier, obesity research and as a scaffold for tissue engineering.
In Vivo: In chemical-induced colonic precancerous lesions in ICR mice, in the 2 weeks preventive experiments, mice fed with a diet containing high molecular weight Chitosan (HMWC) had significant fewer aberrant crypt foci formation than those fed with control diet. As the treatment extended to 6 weeks, both low molecular weight Chitosan (LMWC)- and HMWC-fed mice contained less aberrant crypt foci when compared to control.
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文献和实验Chitosan-Based Nanoparticles as Delivery Systems of Therapeutic Proteins
route remains as a primary strategy for protein administration essentially due to its specific physicochemical properties. However, the research on alternative nonparenteral delivery routes continues. The high molecular weight (MW), hydrophilicity
引物贮存液的摩尔浓度为:76/267,600 = 284 mM 引物浓度的确定 一般合成的寡聚体DNA(Oligo DNA)均以OD260来单位来表示的。所谓OD260值是指在1ml体积1cm光径标准比色杯中,260nm波长下吸光度为1 A260的寡聚体DNA溶液被定义为1 OD260。因此,根据此定义,1OD260单位相当于33ug的寡聚体DNA,从而可根据寡聚体DNA的OD260值及其自身分子量来计算得到摩尔数,以计算不同浓度的溶液。 1.寡聚体DNA分子量(MW)的精确算法
IMMUNOHISTOCHEMISTRY ON Drosophila BRAINS
'' each). 9. Mount in 80 glycerol-PBS. Drosohpila Ringers, per liter: 6.5g NaCl 0.14g KCl 0.2 g NaHCO3 0.12g CaCl2 0.01g NaH2PO4 10X PBS 1.3M NaCl 76.0 g NaCl 0.07M Na2HPO4 9.94g Na2HPO4 (MW=142) H2O to 1L 0.03M NaH2PO4 3.6 g NaH2PO
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