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Somatic Cell Markers:KeratinocytesCDH1 (E-Cadherin),GJB2 (CX26),KRT15,NUMB.
Blood Stem Cell:D34.
Fibroblasts:OL1A1,NCAM1.
Neuronal Stem Cell:MX2,FABP7,NES,OLIG2.
Cardiomyocytes:ECAM1.
Germ Cells:YCP3.
Induced Pluripotent Stem Cells:Induced Pluripotent Stem Cell MarkersDNMT3B,PODXL,ZFP42.
Other Induced Pluripotent Stem Cell Related Genes:CTC1,ALDH1A1 (RALDH1),ALDH2,APC,BGLAP,
BMP2,BRIX1,CCNE1,CD9,CDH2(N-Cadherin),COL2A1,COL9A1,EP300,FGF4,FGFR1,FOXD3,GABRB3,GJA1 (CX43),GRB7,HDAC2,KAT2A,KAT7,KAT8,LEFTY1,LEFTY2,NODAL,PARD6A,REST,RUNX2,TERT.
Reprogramming Factors: KLF4,MYC,POU5F1 (OCT4),SOX2.
Other Reprogramming Factors: ESRRB,LIN28A,MYCN,NANOG,NR5A2.
Reprogramming Enhancers & Inhibitors: AICDA (AID),TP53 (p53),UTF1.
Embryonic Stem Cell Markers: ALPL,GDF3 (VGR-2),TDGF1,TERT.
Other Embryonic Stem Cell Related Genes: CCNA2,CDC42,CDK1,DPPA2,DPPA3,FGF2 (BFGF),HSPA9,
MYBL2,OTX2,SOX15,TBX3,TCF3.
Pluripotency Markers: ALPL,DNMT3B,FGF4,FOXD3,GDF3 (VGR-2),LEFTY1,LEFTY2,NODAL,PODXL,UTF1,
ZFP42.
Early Differentiation Markers: EctodermCOL1A1,NCAM1,NES,PAX6,TUBB3.
Mesoderm: CD34,GATA2,HAND1,MESP1,PECAM1,RUNX1 (AML1).
Endoderm: FOXA2 (HNF3B),GATA4,HNF4A,SOX17.
Housekeeping Gene: NAT1.
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文献和实验Strategies to Generate Induced Pluripotent Stem Cells
of a four transcription factor cocktail. Following this initial study numerous groups have described protocols to generate induced pluripotent stem cells (iPSCs). These protocols have simplified the reprogramming strategy by employing polycistronic reprogramming cassettes
Neural Differentiation of Induced Pluripotent Stem Cells
The great potential of induced pluripotent cells (iPS) cells is that it allows the possibility of deriving pluripotent stem cells from any human patient. Generation of patient-derived stem cells serves as a great source for developing cell
Cryopreservation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
Until now, it has been problematic to obtain high survival rates after thawing of human embryonic stem cells (hESCs) and later also induced pluripotent stem cells (iPSCs). Already in 1994, Freshner and �coworkers established the conventional
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