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文献和实验Protein Engineering of Interferon Alphas
Interferon (IFN)-αs constitute a family of proteins exhibiting high degree of homology in primary, secondary, and tertiary structure and display a high level of species specificity in their biological properties. However, small structural
移位到胞核,如干扰素刺激的基因因子2(interferon-stimulated gene fac-tor 2,ISGF2)和γ-干扰素激活因子(gamma-interferon activation factor,GAF或STAT91)结合到IFN基因启动子中两个称之为γ干扰素活化点(gamma-interferon activation site,GAS)和干扰素刺激的反应元件(interferon-stimulated response element,ISRE)的位置上。IFN-γ可促进
Methods for Studying Interferon Tau Stimulated Genes
Interferon (IFN)τ, a Type I IFN produced by the conceptus trophectoderm, is the pregnancy recognition signal in ruminants that prevents development of the endometrial luteolytic mechanism. In addition, IFNτ acts in a paracrine manner
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