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文献和实验Effect of Cyclopamine on Xenopus laevis embryos
to survive due to serious brain defects. Research performed by Michael K. Cooper and his associates showed that the presence of cyclopamine affects the signaling pathway of SHH in the early chick embryo. They claimed that cyclopamine acts as a class
, Germany. 5Samuel Lunenfeld Research Institute, Mount Sinai Hospital, 600 University Avenue, Toronto, Ontario, M5G 1X5, Canada. 6Department of Molecular Genetics, University of Toronto, Toronto, Ontario, M5S 1A8, Canada. 7German Cancer Research
Tetraploid Complementation Assay
of cell fate during mouse development. This method can speed up the production of genetically modified strains directly from hybrid ES cells. The Transgenic facility at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital and more recently
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