biorelevant特约代理商|现货 促销 FFF02 F

biorelevant特约代理商|FFF02 FaSSIF/FeSSIF/FaSSGF 口服药物肠溶液

FaSSIF/FeSSIF/FaSSGF是一种胆汁盐（牛磺酸钠）与卵磷脂以4：1的摩尔比配制的复合物，这种复合物能较好地模拟出不同状态下人类胃肠道的液体成分（具体配制方法可电询）

产地：USA (美国原装进口）
品牌：biorelevant 公司
货号：FFF02
规格：70G/瓶
存储条件：常温
库存：具体电询

Product Description

FaSSIF, FeSSIF and FaSSGF are dissolution media that simulate human gut fluids:

FaSSIF: Fasted State Simulated Intestinal Fluid  空腹状态模拟肠液
FeSSIF: Fed State Simulated Intestinal Fluid    进食状态模拟肠液
FaSSGF: Fasted State Simulated Gastric Fluid   空腹状态模拟胃液

They contain physiological surfactants (bile salts and lecithin) present in the gastrointestinal tract to simulate these fluids much more accurately than conventional dissolution media.

We’ve been producing FaSSIF/FeSSIF/FaSSGF (originally known as ‘SIF Powder’) for more than a decade and it’s trusted by the 10 biggest Pharmaceutical companies in the world as the industrial standard for preparing biorelevant test media. Its versatility and ease of use make it the perfect introduction to biorelevant testing. Here’s why the product is so useful to both new and generic developers of oral drugs:

*In vitro solubility results in biorelevant media help establish a relationship between the biopharmaceutical properties of an oral drug and in vivo absorption

*In vitro dissolution results in biorelevant media can enable drug developers to identify test formulations with superior dissolution profiles

*Ideal for use in USP 1 or USP 2 dissolution apparatus (we recommend 900mL of media per vessel)

*Drug analysis can be carried out by HPLC

*Standardized preparation method is extremely fast and simple and results in highly reproducible media every time

*Get customized instructions explaining how to make different FaSSIF/FeSSIF/FaSSGF volumes from our ‘Media Preparation Tool’ (see above)