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文献和实验Determination of Cancer Allelotype
The term “allelotype” was first used by Vogelstein and colleagues (1 ), in analogy to karyotype, to describe a newly developed molecular analysis that surveyed chromosomal loss and/or aberration in a panel of human colorectal tumors
Breast Cancer Screening and Biomarkers
in detecting early breast cancer. Ideally, such a biomarker panel should be able to detect breast cancer in asymptomatic patients, even in the setting of normal mammogram and physical examination results.
Using Live Cells to Generate Aptamers for Cancer Study
, we have generated a panel of aptamers for the specific recognition of leukemia cells, and we report the results in this study. The selected aptamers were found to bind to target cells with an equilibrium dissociation constant (K d ) in the nanomolar-to-picomolar
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