- ￥730 - 950
- TargetMol
- 美国
- T3S0209
- 2025年07月14日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Vincristine
- 库存：
10
- 供应商：
TargetMol
- CAS号：
57-22-7
- 规格：
1 mL/20 mg
| 规格： | 1 mL | 产品价格： | ￥730.0 |
|---|---|---|---|
| 规格： | 20 mg | 产品价格： | ￥950.0 |
Product Introduction
Bioactivity
英文名:Vincristine
描述:Vincristine is an alkaloidal natural product that binds to microtubule proteins and inhibits the formation of microtubules, thereby inhibiting mitosis in tumor cells. Vincristine is used as a microtubule destabilizing agent in research studies for the treatment of hematologic neoplasms such as leukemias and lymphomas, as well as in studies related to sarcomas in children.
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文献和实验与长春花碱（ vinblastine）、泛洛洛新及泛洛洗汀等一起含在蔓长春花（ Vinca major）中的生物碱。具有使细胞分裂（有丝分裂）在中期停止的作用，这与秋水仙素相似，但其作用比秋水仙素更强。与秋水仙素一样可以与微管蛋白结合而抑制其生物活性，但结合部位不同。另外它与秋水仙素不同的是对微管蛋白以外的蛋白质如肌动蛋白及 10纳米细丝蛋白等也起作用。在临床医学上作为抗癌剂之一而被应用，特别是对造血器官的肿瘤比较有效。
A Rat Pain Model of Vincristine-Induced Neuropathy
Vincristine belongs to the family of vinca alkaloids used for treatment of malignant tumors. Clinical application of these agents is often associated with dose-dependent painful neuropathy due to damages to the peripheral axons. A rat model
Atomic Force Microscopy Studies on Circular DNA Structural Changes by Vincristine and Aspirin
In this chapter, we have presented materials and methods to study the interaction between DNA and small molecule drugs by AFM. The detailed AFM imaging of the circular DNA after incubation with �various concentrations of vincristine
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