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- TargetMol
- 美国
- TP2056
- 2025年07月11日
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- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
Acetyl-Calpastatin(184-210)(human)
- 库存：
10
- 供应商：
TargetMol
- CAS号：
123714-50-1
- 规格：
1 mg
Product Introduction
Bioactivity
英文名:Acetyl-Calpastatin(184-210)(human)
描述:Selective calpain inhibitor. Strongly inhibits calpain I (Ki = 0.2 nM) and II but does not inhibit papain, trypsin and cathepsin L (Ki = 6 μM). Increases secretion of amyoid β-protein (Aβ) 42, Aβ40 and Aβ42 ratio.
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文献和实验Preparation of Calpastatin Samples for Western Blotting
% (5 ). Full-length calpastatins (made up of domains L and 1–4) from most tissues of human, rabbit, pig, and others, migrate as 110–120 kDa proteins in SDS-PAGE. However calpastatin from bovine heart migrates as a protein of 140–170 kDa (1 ), probably
Transcriptional Activation Analysis by the Chloramphenicol Acetyl Transferase (CAT) Enzyme Assay
reporter genes can be used to measure transcription activity, such as chloramphenicol acetyl transferase (CAT), luciferase, (β-galactosidase, and human growth hormone (7 ). To examine the transcription enhancement activity of a putative promoter/enhancer
Therapeutic Human Monoclonal Antibodies Against Cancer
. There are a number of monoclonal antibodies used in the treatment of malignancies; in fact, three of the top five grossing antibodies (bevacizumab, trastuzumab, and rituximab) are used in oncology Scolnik (mAbs 1:179–184, 2009).
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