- ￥582 - 7490
- TargetMol
- 美国
- T16344
- 2025年08月01日
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- 详细信息
- 文献和实验
- 技术资料
- 保存条件：
零下80~20°C
- 保质期：
Powder: -20°C for 3 years In solvent: -80°C for 2 years
- 英文名：
NS-2028
- 库存：
10
- 供应商：
TargetMol
- CAS号：
204326-43-2
- 规格：
10 mg/1 mg/5 mg/25 mg/2 mg/1 mL/50 mg/100 mg
| 规格： | 10 mg | 产品价格： | ￥2180.0 |
|---|---|---|---|
| 规格： | 1 mg | 产品价格： | ￥582.0 |
| 规格： | 5 mg | 产品价格： | ￥1230.0 |
| 规格： | 25 mg | 产品价格： | ￥3680.0 |
| 规格： | 2 mg | 产品价格： | ￥848.0 |
| 规格： | 1 mL | 产品价格： | ￥1320.0 |
| 规格： | 50 mg | 产品价格： | ￥5330.0 |
| 规格： | 100 mg | 产品价格： | ￥7490.0 |
Product Introduction
Bioactivity
英文名:NS-2028
描述:NS-2028 is a highly selective soluble Guanylyl Cyclase (sGC) inhibitor (IC50: 30 nM and 200 nM for basal and NO-stimulated enzyme activity). It is commonly used in the research of nitric oxide signaling pathways. NS-2028 inhibits soluble Guanylyl Cyclase activity in homogenates of mouse cerebellum and neuronal NO synthase (IC50: 17 nM and 20 nM). NS-2028 inhibits 3-morpholino-sydnonimine (SIN-1)-elicited formation of cyclic GMP in human cultured umbilical vein endothelial cells (IC50: 30 nM). NS-2028 inhibits NO-dependent relaxant responses in non-vascular smooth muscle completely (1 μM). NS-2028 decreases vascular endothelial growth factor-induced angiogenesis and permeability.
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文献和实验NS5A Phosphorylation and Hyperphosphorylation
NS5A phosphorylation can be studied in two ways: in living cells and in vitro. The former has several advantages: NS5A phosphorylation takes place in a cellular background and therefore might mimic more closely the real in vivo situation
Preparation and Handling of Hepatitis C Viral Proteins NS3 and NS5B for Structural Studies
HCV is a small positive-strand RNA virus responsible for a considerable proportion of acute and chronic hepatitis in humans. Although all HCV enzymes are, in theory, equally appropriate for therapeutic intervention, the NS3-NS4A serine
Expression and Characterization of the HCV NS2 Protease
and cell-free expression systems have shown that host signalase is responsible for cleavages between the structural proteins and at the N-terminus of NS2 (1 –4 ), whereas a chymotrypsin-like serine protease located in the N-terminal region of NS
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